The American College of Cardiology/American Heart Association (ACC/AHA) Cholesterol and Primary Prevention Guidelines included South Asian ethnicity among their “risk-enhancing” factors. However, the current risk calculators widely used in clinical practice often underestimate risk in this population, particularly for those at borderline or intermediate risk.
The approach needs to be individualized as significant differences are noted in the incidence of heart disease, diabetes, stroke and kidney disease development based on ethnic groups, lifestyle, and individual risk factors. However, often, patients are provided risk assessment and treatment plans that do not account for an individual’s background and personalized needs.
For example, measuring low-density lipoprotein (LDL) cholesterol levels, usually considered a gold standard for future risk assessment, may not be adequate for this population. Often, individuals of South Asian origin suffer a heart attack, or stroke, even with “normal” LDL. However, more in-dept testing with lipoprotein(a) level and other blood markers as well as coronary artery calcium scan can accurately assess the risk in this population.
There are also differing “normal values” of HbA1c (average blood sugar level) and eGFR (a marker of kidney function) for this population which are often not accounted for and require additional testing for precise risk assessment and management.
Through this dedicated program, we aim to provide comprehensive and individualized risk assessment and tailored screening, surveillance, prevention and management plans.