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Neurointerventional radiology (NIR) — also called interventional neuroradiology or endovascular neurosurgery — is a medical specialty that uses minimally invasive, image-guided techniques to diagnose and treat complex diseases of the brain, neck, and spine. Rather than performing traditional “open” surgery (which involves large incisions or drilling into the skull), specialists in this field use high-tech imaging like X-rays and CT scans to navigate tiny tools into the blood vessels of the brain and spine.
Neurointerventional radiologists at Lahey Clinic are at the leading-edge of this field. Our facilities are equipped with modern, state-of-the-art technology to provide advanced neurointerventional care, as well as education and training for future experts in neuroradiology.
Our multidisciplinary team consists of internationally renowned interventional neuroradiologists and neurosurgeons who closely work with neurologists, ENT physicians, and radiation specialists allowing us to encompass a wide range of expertise and treatment options for neurovascular diseases and minimally invasive percutaneous spine procedures. Our group is led by Timo Krings, Chair and Division Chief of Neurointerventional Radiology.
In this video, members of our Neurointerventional Radiology team explain who they are, what they do, and how they care for patients using minimally invasive techniques.
Our team provides Neurointerventional Radiology services for conditions affecting the brain, neck, and spine. Conditions we treat include:
An acute ischemic stroke occurs when a blood clot blocks an artery supplying blood to the brain. When the "pipe" is blocked, the brain cells beyond that point are starved of oxygen and nutrients. Without immediate help, these brain cells can begin to die within minutes.
Most ischemic strokes are caused by one of two things: a blood clot that forms inside a narrowed brain artery (thrombosis), or a clot that forms elsewhere in the body—often the heart—and travels up to the brain (embolism). Common risk factors include high blood pressure, high cholesterol, smoking, diabetes, or heart conditions like atrial fibrillation (AFib).
Diagnosis happens very quickly in the emergency room. Doctors use rapid imaging, such as a CT scan or MRI, to look at the brain and its blood vessels. These scans help the team confirm if there is a blockage and exactly where it is located.
Yes. This is a medical emergency. “Time is brain,” meaning every minute the artery stays blocked, more brain cells are lost. Immediate treatment is the best way to prevent permanent disability, such as paralysis or loss of speech, and to save the patient's life.
There are two primary ways our team clears the blockage:
In order to prevent stroke we can treat one of the most common causes: arterial narrowing or stenosis, the most common of which afflicts the carotid arteries.
Carotid artery stenosis (also called carotid artery disease) is a narrowing of the two large arteries on either side of your neck. These vital vessels carry oxygen-rich blood from your heart to your brain. The narrowing is typically caused by a buildup of plaque—a sticky substance made of fat, cholesterol, and calcium—on the inner walls of the artery.
Plaque buildup, or atherosclerosis, develops slowly over many years. While it is a natural part of aging, certain factors can speed up the process.
Common risk factors include:
Since this condition often has no symptoms in its early stages, it is frequently discovered during a routine checkup if a doctor hears a "whooshing" sound (called a bruit) through a stethoscope. To confirm the diagnosis and measure the narrowing, we use advanced imaging such as:
Yes, if the narrowing is significant. Carotid stenosis is a major cause of stroke. A stroke can happen if the artery becomes completely blocked or if a small piece of plaque breaks off and travels into the brain. Treatment is recommended to "clean" or "open" the artery to prevent a future stroke, especially if you have already experienced “warning signs” like a TIA (mini-stroke).
At Lahey, our team offers several ways to restore healthy blood flow:
A brain aneurysm (also called a cerebral or intracranial aneurysm) is a weak or thin spot on a blood vessel in the brain that balloons out and fills with blood. While many aneurysms go unnoticed, the danger is that they can leak or rupture, causing life-threatening bleeding into the space around the brain (a subarachnoid hemorrhage).
Aneurysms usually develop over time rather than being present at birth. They often form at “forks” in the arteries where the blood flow is strongest. Risk factors that can weaken artery walls include:
Many aneurysms are found incidentally when a patient is getting a scan for an unrelated reason, like a headache or an injury. At Lahey, we use high-resolution imaging to find and measure them: such MRA or CTA Scans: which provide non-invasive 3D pictures of the blood vessels.
Not every aneurysm requires immediate management. If an aneurysm is very small and hasn't ruptured, we may simply “watch and wait” with regular imaging. However, if the aneurysm is large, growing, or has a shape that suggests a high risk of bursting, treatment is necessary to prevent a devastating stroke. If an aneurysm has already ruptured, it is a medical emergency that requires instant treatment.
Our team specializes in the most advanced, minimally invasive endovascular treatments:
An Arteriovenous Malformation (AVM) is a tangle of abnormal blood vessels that connects arteries and veins in the brain or spine. Normally, arteries carry oxygen-rich blood to the brain through tiny capillaries, which then transition into veins to carry blood back to the heart. In an AVM, the blood bypasses the capillaries and flows directly from arteries to veins at high pressure. This can cause the vessels to rupture or “steal” blood away from healthy brain tissue.
There is no single cause of an AVM. They cannot spread, and there is nothing you can do or change that will prevent one from occurring. There are some genetic causes. Some rare types of AVMs run in families. These are associated with a condition called Hereditary Haemorrhagic Telangiectasia, or Osler-Weber-Rendu Syndrome.
AVMs are often discovered after a person experiences a seizure, a sudden severe headache, or symptoms similar to a stroke. To see the tangle clearly, we use noninvasive imaging followed by a cerebral angiogram which is the most important test for planning treatment. Our specialists thread a catheter to the brain to map exactly how the blood enters and leaves the AVM.
The main goal of treatment is to prevent a brain hemorrhage (bleeding). Because AVMs involve high-pressure blood flowing through weak vessels, they have a risk of rupturing over time. If an AVM is in a very deep or “eloquent” part of the brain (responsible for speech or movement), our team carefully weighs the risks of treatment versus the risk of leaving it alone. If it has already bled, it almost always requires treatment to prevent a second, more dangerous bleed.
Because AVMs are complex, the Lahey team often uses a multimodal approach (more than one type of treatment):
To learn more, you can watch videos on spinal AVMs and brain AVMs.
A dural arteriovenous fistula (dAVF) is an abnormal connection between an artery and a vein in the tough, protective covering of the brain or spinal cord (the dura mater). Normally, high-pressure blood from arteries passes through tiny capillaries before entering low-pressure veins. In a dAVF, the artery connects directly to the vein. This creates a high-pressure "short circuit" that can cause the veins to swell, leak, or back up, potentially leading to brain or spinal cord injury.
dAVFs are usually acquired later in life. They often develop after a blood clot forms in one of the brain’s large drainage veins (venous sinus thrombosis). The body tries to bypass the blockage by growing new, abnormal vessel connections. Other triggers can include head trauma, previous brain surgery, or chronic ear infections, though sometimes the cause remains unknown.
The symptoms of a dAVF can be unique. Patients often hear a rhythmic "whooshing" or "pulsing" sound in one ear that matches their heartbeat (called pulsatile tinnitus). Others may experience vision changes or headaches. To diagnose it, we use MR and CT as well as a diagnostic angiogram which is the most critical test. Our specialists thread a catheter to the site to precisely map the "fistula" (the connection point) and determine how the blood is draining.
It depends on the "drainage pattern." If the blood is draining into the large veins of the skull, it may be low-risk and only require monitoring. However, if the blood is backing up into the smaller, fragile veins on the surface of the brain (cortical venous reflux), the risk of brain hemorrhage or stroke is much higher. In these cases, treatment is necessary to prevent permanent damage.
Our team specializes in closing these abnormal connections from the inside:
To learn more, watch a video on dural arteriovenous fistulas.
Intracranial hypotension is a condition where the pressure of the fluid surrounding your brain and spinal cord—called Cerebrospinal Fluid (CSF)—is too low. Usually, this happens because of a "leak" in the tough outer membrane (the dura) of the spine. A specific, newly discovered type of leak is the CSF-Venous Fistula, where the fluid doesn't just leak into the body; it drains directly and abnormally into a nearby vein, like a sink left running with the drain open.
Most cases occur spontaneously, meaning they happen without a clear injury. It can be caused by a tiny bone spur on the spine that pokes a hole in the dura, or by a weakness in the dural membrane itself (sometimes associated with connective tissue disorders). In the case of a CSF-Venous Fistula, it is an abnormal connection that develops over time, though the exact reason why these connections form is still being studied by specialists.
The hallmark symptom is a positional headache—a headache that feels much worse when you are standing up and significantly improves or disappears when you lie flat. Because these leaks can be microscopic, they are often missed on standard scans. At Lahey, we use highly specialized imaging to find them: including Brain and Spine MRI: To look for signs that the brain is "sagging" due to low pressure and Ultra-High-Resolution CT Myelogram as the most advanced way to pinpoint a tiny fistula or leak point.
Yes, if the symptoms are affecting your quality of life. While not usually life-threatening, the chronic, severe headaches can be disabling. In some cases, long-term low pressure can lead to complications like collections of fluid or blood around the brain (subdural hematomas) or extreme lethargy.
Our neurointerventional team offers targeted, minimally invasive solutions:
Hear about one patient’s experience with SIH.
To learn more, watch a video on CSF leaks and intracranial hypotension.
Idiopathic Intracranial Hypertension (IIH), previously known as pseudotumor cerebri, is a condition where the pressure of the fluid around your brain (cerebrospinal fluid or CSF) becomes too high. The name "pseudotumor" comes from the fact that it causes symptoms similar to a brain tumor—such as severe headaches and vision changes—even though no tumor is present.
"Idiopathic" means the exact cause is unknown. However, it is most common in women of childbearing age and is strongly linked to being overweight or recent weight gain. Experts believe it happens when your body either produces too much CSF or, more commonly, doesn't reabsorb it back into the bloodstream properly. Certain medications, such as some antibiotics or steroids, can also increase the risk.
Because IIH mimics other conditions, diagnosis involves several steps to rule out other causes:
Yes. While not life-threatening, untreated IIH can lead to permanent vision loss or even blindness because the constant pressure damages the optic nerves. It also causes chronic, disabling headaches that significantly impact quality of life.
The goal is to lower the pressure and protect your sight. At Lahey, our team uses a tiered approach:
Pulsatile tinnitus is a rhythmic thumping, swooshing, or whooshing sound in your ear that beats in time with your heartbeat. Unlike common tinnitus, which is often a constant ringing, this version is usually a physical sound caused by turbulent blood flow in the vessels near your ear. It can be soft and intermittent or loud enough to disrupt sleep and daily concentration.
Pulsatile tinnitus is not a disease itself but a symptom of an underlying vascular or structural issue. It occurs when blood flow changes from a smooth, quiet stream to a noisy, turbulent one. Common causes include:
Because the cause can be complex, our team uses a systematic map of your blood vessels: We check if the sound changes when you turn your head or if it can be heard by a doctor using a stethoscope (objective tinnitus). MRI/MRA or CT/CTA/CTV scans provide high-resolution images of the brain’s anatomy and blood flow.
It depends on the cause. For some, it is a benign but annoying sound. However, in other cases, it can be a warning sign of more serious conditions. If the sound is debilitating or linked to a dangerous vascular issue, treatment is recommended.
Our goal is to silence the sound by fixing the underlying blood flow problem:
To learn more, watch a video on tinnitus.
Note: This is an experimental treatment option, and we maintain very strict inclusion criteria for candidates.
A migraine is a complex neurological condition characterized by intense, throbbing headaches often accompanied by nausea and sensitivity to light or sound. While traditional treatments focus on brain chemistry, our team is exploring an innovative approach called Middle Meningeal Artery (MMA) Embolization. This procedure targets the blood vessels in the lining of the brain (the dura) that may play a role in triggering or worsening chronic migraine pain.
The exact cause of migraines is still being researched, but they are believed to result from a combination of genetic factors and environmental triggers. These triggers can cause the nervous system to overreact, leading to inflammation and the dilation of blood vessels in the brain’s protective covering, which sends intense pain signals to the brain.
Migraines are typically diagnosed by a neurologist based on your medical history, symptoms, and the frequency of your attacks. To determine if you are a candidate for our experimental embolization procedure, we perform imaging to rule out other causes of headaches.
Treatment is considered when migraines become chronic (occurring 15 or more days per month) and significantly interfere with your work, family life, and overall well-being. Because this specific procedure is experimental, it is reserved for patients who have not found relief through standard therapies.
Most migraines are managed with lifestyle changes, oral medications, or Botox injections. However, for a very specific group of patients, our neurointerventional team offers MMA Embolization (Experimental).
Using a minimally invasive catheter-based approach, we navigate to the Middle Meningeal Artery and use medication or liquid agents to reduce the blood flow to the dural lining. The goal is to "calm" the overactive pain signals originating from these vessels.
Strict Inclusion Criteria: Because this is an emerging therapy, candidates must have failed multiple conventional treatments and undergo a rigorous screening process by both our neurointerventionalists and headache specialists to ensure the highest level of safety and appropriateness.
A vertebral compression fracture (VCF) occurs when one of the bones in your spine (a vertebra) collapses or cracks. This most often happens in the mid-to-lower back. Unlike a clean break in an arm or leg bone, a compression fracture causes the bone to lose its height and take on a wedge shape, which can lead to a hunched posture and significant back pain.
The most common cause is osteoporosis, a condition that thins and weakens bones as we age. When bones are very fragile, even everyday activities like reaching, coughing, or a minor trip can cause a fracture. Other causes include:
If you have sudden, severe back pain—especially if it gets worse when standing or walking and feels better when lying down—we use imaging (CT, MR, x-Ray) to look for a fracture.
While some fractures heal on their own with rest, bracing, and pain medication, many do not. If left untreated, a VCF can lead to chronic pain, decreased mobility, and a stooped posture (kyphosis). If the pain is severe enough to keep you from walking or performing daily tasks, a minimally invasive procedure is often recommended to stabilize the bone.
Our team specializes in "cementing" the bone to stop the pain and restore stability:
Basivertebral Nerve (BVN) Ablation is a minimally invasive, outpatient procedure designed to treat chronic vertebrogenic low back pain. While many back pains come from discs or muscles, vertebrogenic pain actually comes from the vertebral bones themselves. This procedure uses radiofrequency energy (heat) to “turn off” the basivertebral nerve, preventing it from carrying pain signals from the spine to the brain.
Vertebrogenic pain is caused by the wear and tear of the “endplates” — the areas where your spinal discs connect to the vertebral bones. Over time, these endplates can become inflamed or damaged due to aging, heavy lifting, or repetitive stress. This inflammation irritates the basivertebral nerve, leading to chronic, deep, aching pain in the lower back.
We identify candidates using very specific criteria on an MRI. We look for “Modic changes” — distinctive signs of inflammation or swelling in the vertebral bone marrow near the endplates. If you have chronic low back pain for at least six months that hasn't responded to conservative treatments (like physical therapy or injections), and your MRI shows these specific changes, you may be a candidate.
This condition is not life-threatening, but the pain can be debilitating. If your back pain limits your ability to work, exercise, or enjoy daily life, and you want a long-term solution that does not involve major spinal fusion surgery or long-term pain medication, BVN ablation is a highly effective option.
At Lahey, our neurointerventional specialists perform this procedure using the Intracept System:
We welcome physician referrals, giving us the opportunity to provide excellent care for your patients.
Our team offers a range of education and training opportunities, including observerships, preceptorships, and neurointerventional fellowships.